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Survey of the Heritability and Sparse Architecture of Gene Expression Traits across Human Tissues

Understanding the genetic architecture of gene expression traits is key to elucidating the underlying mechanisms of complex traits. Here, for the first time, we perform a systematic survey of the heritability and the distribution of effect sizes across all representative tissues in the human body. W...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:PLoS Genet
Päätekijät: Wheeler, Heather E., Shah, Kaanan P., Brenner, Jonathon, Garcia, Tzintzuni, Aquino-Michaels, Keston, Cox, Nancy J., Nicolae, Dan L., Im, Hae Kyung
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5106030/
https://ncbi.nlm.nih.gov/pubmed/27835642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006423
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