A gene-based association method for mapping traits using reference transcriptome data

Genome-wide association studies (GWAS) have identified thousands of variants robustly associated with complex traits. However, the biological mechanisms underlying these associations are, in general, not well understood. We propose a gene-based association method called PrediXcan that directly tests...

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Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Gamazon, Eric R., Wheeler, Heather E., Shah, Kaanan P., Mozaffari, Sahar V., Aquino-Michaels, Keston, Carroll, Robert J., Eyler, Anne E., Denny, Joshua C., Nicolae, Dan L., Cox, Nancy J., Kyung Im, Hae
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552594/
https://ncbi.nlm.nih.gov/pubmed/26258848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3367
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