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Characterization of Novel Molecular Mechanisms Favoring Rac1 Membrane Translocation
The Rac1 GTPase plays key roles in cytoskeletal organization, cell motility and a variety of physiological and disease-linked responses. Wild type Rac1 signaling entails dissociation of the GTPase from cytosolic Rac1-Rho GDP dissociation inhibitor (GDI) complexes, translocation to membranes, activat...
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Publicado no: | PLoS One |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5105943/ https://ncbi.nlm.nih.gov/pubmed/27835684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166715 |
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