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A palmitoylation switch mechanism regulates Rac1 function and membrane organization
The small GTPase Rac1 plays important roles in many processes, including cytoskeletal reorganization, cell migration, cell-cycle progression and gene expression. The initiation of Rac1 signalling requires at least two mechanisms: GTP loading via the guanosine triphosphate (GTP)/guanosine diphosphate...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3273400/ https://ncbi.nlm.nih.gov/pubmed/22157745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.446 |
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