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A palmitoylation switch mechanism regulates Rac1 function and membrane organization

The small GTPase Rac1 plays important roles in many processes, including cytoskeletal reorganization, cell migration, cell-cycle progression and gene expression. The initiation of Rac1 signalling requires at least two mechanisms: GTP loading via the guanosine triphosphate (GTP)/guanosine diphosphate...

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Detalhes bibliográficos
Main Authors: Navarro-Lérida, Inmaculada, Sánchez-Perales, Sara, Calvo, María, Rentero, Carles, Zheng, Yi, Enrich, Carlos, Del Pozo, Miguel A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273400/
https://ncbi.nlm.nih.gov/pubmed/22157745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.446
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