Coronin 1A promotes a cytoskeletal-based feedback loop that facilitates Rac1 translocation and activation

The activation of the Rac1 GTPase during cell signalling entails its translocation from the cytosol to membranes, release from sequestering Rho GDP dissociation inhibitors (RhoGDI), and GDP/GTP exchange. In addition to those steps, we show here that optimal Rac1 activation during cell signalling req...

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Detalhes bibliográficos
Main Authors: Castro-Castro, Antonio, Ojeda, Virginia, Barreira, María, Sauzeau, Vincent, Navarro-Lérida, Inmaculada, Muriel, Olivia, Couceiro, José R, Pimentel-Muíños, Felipe X, del Pozo, Miguel A, Bustelo, Xosé R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209784/
https://ncbi.nlm.nih.gov/pubmed/21873980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.310
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