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Coronin 1A promotes a cytoskeletal-based feedback loop that facilitates Rac1 translocation and activation
The activation of the Rac1 GTPase during cell signalling entails its translocation from the cytosol to membranes, release from sequestering Rho GDP dissociation inhibitors (RhoGDI), and GDP/GTP exchange. In addition to those steps, we show here that optimal Rac1 activation during cell signalling req...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3209784/ https://ncbi.nlm.nih.gov/pubmed/21873980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.310 |
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