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Joint Prediction of the Effective Population Size and the Rate of Fixation of Deleterious Mutations

Mutation, genetic drift, and selection are considered the main factors shaping genetic variation in nature. There is a lack, however, of general predictions accounting for the mutual interrelation between these factors. In the context of the background selection model, we provide a set of equations...

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Vydáno v:Genetics
Hlavní autoři: Santiago, Enrique, Caballero, Armando
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105856/
https://ncbi.nlm.nih.gov/pubmed/27672094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.188250
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