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The Effects of Variable Mutation Rates across Sites on the Phylogenetic Estimation of Effective Population Size or Mutation Rate of DNA Sequences

Multiple hits at some sites of human mitochondrial DNA sequences suggest that the commonly assumed infinite-sites model can be violated. Under the neutral Wright-Fisher model without recombination and population subdivision, we investigated, by computer simulations, the effect of multiple hits on th...

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Detalhes bibliográficos
Main Authors: Deng, H. W., Fu, Y. X.
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1207618/
https://ncbi.nlm.nih.gov/pubmed/8913767
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