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Genetic and pharmacological inhibition of CDK9 drives neutrophil apoptosis to resolve inflammation in zebrafish in vivo

Neutrophilic inflammation is tightly regulated and subsequently resolves to limit tissue damage and promote repair. When the timely resolution of inflammation is dysregulated, tissue damage and disease results. One key control mechanism is neutrophil apoptosis, followed by apoptotic cell clearance b...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hoodless, Laura J., Lucas, Christopher D., Duffin, Rodger, Denvir, Martin A., Haslett, Christopher, Tucker, Carl S., Rossi, Adriano G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105078/
https://ncbi.nlm.nih.gov/pubmed/27833165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36980
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