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Genetic and pharmacological inhibition of CDK9 drives neutrophil apoptosis to resolve inflammation in zebrafish in vivo

Neutrophilic inflammation is tightly regulated and subsequently resolves to limit tissue damage and promote repair. When the timely resolution of inflammation is dysregulated, tissue damage and disease results. One key control mechanism is neutrophil apoptosis, followed by apoptotic cell clearance b...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Hoodless, Laura J., Lucas, Christopher D., Duffin, Rodger, Denvir, Martin A., Haslett, Christopher, Tucker, Carl S., Rossi, Adriano G.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105078/
https://ncbi.nlm.nih.gov/pubmed/27833165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36980
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