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CDK9 and its repressor LARP7 modulate cardiomyocyte proliferation and response to injury in the zebrafish heart

Cyclin dependent kinase (Cdk)9 acts through the positive transcription elongation factor-b (P-TEFb) complex to activate and expand transcription through RNA polymerase II. It has also been shown to regulate cardiomyocyte hypertrophy, with recent evidence linking it to cardiomyocyte proliferation. We...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Matrone, Gianfranco, Wilson, Kathryn S., Maqsood, Sana, Mullins, John J., Tucker, Carl S., Denvir, Martin A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696495/
https://ncbi.nlm.nih.gov/pubmed/26542022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.175018
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