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The cytotoxic synergy of nanosecond electric pulses and low temperature leads to apoptosis

Electroporation by nanosecond electric pulses (nsEP) is an emerging modality for tumor ablation. Here we show the efficient induction of apoptosis even by a non-toxic nsEP exposure when it is followed by a 30-min chilling on ice. This chilling itself had no impact on the survival of U-937 or HPAF-II...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Muratori, Claudia, Pakhomov, Andrei G., Gianulis, Elena C., Jensen, Sarah Damsbo, Pakhomova, Olga N.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5104977/
https://ncbi.nlm.nih.gov/pubmed/27833151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36835
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