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The cytotoxic synergy of nanosecond electric pulses and low temperature leads to apoptosis

Electroporation by nanosecond electric pulses (nsEP) is an emerging modality for tumor ablation. Here we show the efficient induction of apoptosis even by a non-toxic nsEP exposure when it is followed by a 30-min chilling on ice. This chilling itself had no impact on the survival of U-937 or HPAF-II...

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Detalles Bibliográficos
Publicado en:Sci Rep
Autores principales: Muratori, Claudia, Pakhomov, Andrei G., Gianulis, Elena C., Jensen, Sarah Damsbo, Pakhomova, Olga N.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5104977/
https://ncbi.nlm.nih.gov/pubmed/27833151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36835
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