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The cytotoxic synergy of nanosecond electric pulses and low temperature leads to apoptosis

Electroporation by nanosecond electric pulses (nsEP) is an emerging modality for tumor ablation. Here we show the efficient induction of apoptosis even by a non-toxic nsEP exposure when it is followed by a 30-min chilling on ice. This chilling itself had no impact on the survival of U-937 or HPAF-II...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Muratori, Claudia, Pakhomov, Andrei G., Gianulis, Elena C., Jensen, Sarah Damsbo, Pakhomova, Olga N.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5104977/
https://ncbi.nlm.nih.gov/pubmed/27833151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36835
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