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MicroRNA-199a-5p inhibits cisplatin-induced drug resistance via inhibition of autophagy in osteosarcoma cells

Osteosarcoma (OS) is the most common cancer of the bone. Chemotherapy is commonly used for the clinical treatment of OS. However, chemoresistance to cisplatin [also known as diamminedichloridoplatinum (II) (DDP)] is a major obstacle for OS therapy, the underlying mechanism of which is not fully unde...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncol Lett
Hauptverfasser: Li, Yusheng, Jiang, Wei, Hu, Yuling, Da, Zixun, Zeng, Chao, Tu, Min, Deng, Zhenhan, Xiao, Wenfeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5104258/
https://ncbi.nlm.nih.gov/pubmed/27895792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.5172
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