MicroRNA-22 mediates the cisplatin resistance of osteosarcoma cells by inhibiting autophagy via the PI3K/Akt/mTOR pathway

Osteosarcoma (OS) is the most common primary malignant tumor of the bone affecting children and adolescents. Chemotherapy is now considered as a standard component of OS treatment, not only for children, but also for adults. However, chemoresistance continues to pose a challenge to therapy. Inhibiti...

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Vydáno v:Oncol Rep
Hlavní autoři: Meng, Chen-Yang, Zhao, Zhen-Qun, Bai, Rui, Zhao, Wei, Wang, Yu-Xing, Xue, Hui-Qin, Sun, Liang, Sun, Chao, Feng, Wei, Guo, Shi-Bing
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7057943/
https://ncbi.nlm.nih.gov/pubmed/32323781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2020.7492
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