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MicroRNA-127-5p regulates osteopontin expression and osteopontin-mediated proliferation of human chondrocytes

The aim of this study was to determine the specific microRNA (miRNA) that regulates expression of osteopontin (OPN) in osteoarthritis (OA). The potential regulatory miRNAs for OPN messenger RNA (mRNA) were predicted by miRNA prediction programs. Among eight potential regulatory miRNAs, miR-220b, miR...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Tu, Min, Li, Yusheng, Zeng, Chao, Deng, Zhenhan, Gao, Shuguang, Xiao, Wenfeng, Luo, Wei, Jiang, Wei, Li, Liangjun, Lei, Guanghua
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850404/
https://ncbi.nlm.nih.gov/pubmed/27126955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25032
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