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Deficiency of SUMO-specific protease 1 induces arsenic trioxide-mediated apoptosis by regulating XBP1 activity in human acute promyelocytic leukemia

Small ubiquitin-like modifier (SUMO)/sentrin-specific protease 1 (SENP1), a member of the SENP family, is highly expressed in several neoplastic tissues. However, the effect of SENP1 in acute promyelocytic leukemia (APL) has not been elucidated. In the present study, it was observed that SENP1 defic...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncol Lett
Auteurs principaux: Wang, Fei-Fei, Liu, Ming-Zhu, Sui, Yi, Cao, Qing, Yan, Bo, Jin, Mei-Ling, Mo, Xi
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5104160/
https://ncbi.nlm.nih.gov/pubmed/27895727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.5162
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