Metabolic alterations by indoxyl sulfate in skeletal muscle induce uremic sarcopenia in chronic kidney disease

Sarcopenia is associated with increased morbidity and mortality in chronic kidney disease (CKD). Pathogenic mechanism of skeletal muscle loss in CKD, which is defined as uremic sarcopenia, remains unclear. We found that causative pathological mechanism of uremic sarcopenia is metabolic alterations b...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Sato, Emiko, Mori, Takefumi, Mishima, Eikan, Suzuki, Arisa, Sugawara, Sanae, Kurasawa, Naho, Saigusa, Daisuke, Miura, Daisuke, Morikawa-Ichinose, Tomomi, Saito, Ritsumi, Oba-Yabana, Ikuko, Oe, Yuji, Kisu, Kiyomi, Naganuma, Eri, Koizumi, Kenji, Mokudai, Takayuki, Niwano, Yoshimi, Kudo, Tai, Suzuki, Chitose, Takahashi, Nobuyuki, Sato, Hiroshi, Abe, Takaaki, Niwa, Toshimitsu, Ito, Sadayoshi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5103201/
https://ncbi.nlm.nih.gov/pubmed/27830716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36618
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