Indoxyl Sulfate Down-Regulates SLCO4C1 Transporter through Up-Regulation of GATA3

The accumulated uremic toxins inhibit the expression of various renal transporters and this inhibition may further reduce renal function and subsequently cause the accumulation of uremic toxins. However, the precise mechanism of the nephrotoxicity of uremic toxins on renal transport has been poorly...

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Detalhes bibliográficos
Main Authors: Akiyama, Yasutoshi, Kikuchi, Koichi, Saigusa, Daisuke, Suzuki, Takehiro, Takeuchi, Yoichi, Mishima, Eikan, Yamamoto, Yasuaki, Ishida, Ayako, Sugawara, Daiki, Jinno, Daisuke, Shima, Hisato, Toyohara, Takafumi, Suzuki, Chitose, Souma, Tomokazu, Moriguchi, Takashi, Tomioka, Yoshihisa, Ito, Sadayoshi, Abe, Takaaki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706553/
https://ncbi.nlm.nih.gov/pubmed/23874392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066518
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