Dynamic Oligomerization of Integrase Orchestrates HIV Nuclear Entry

Nuclear entry is a selective, dynamic process granting the HIV-1 pre-integration complex (PIC) access to the chromatin. Classical analysis of nuclear entry of heterogeneous viral particles only yields averaged information. We now have employed single-virus fluorescence methods to follow the fate of...

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Published in:Sci Rep
Main Authors: Borrenberghs, Doortje, Dirix, Lieve, De Wit, Flore, Rocha, Susana, Blokken, Jolien, De Houwer, Stéphanie, Gijsbers, Rik, Christ, Frauke, Hofkens, Johan, Hendrix, Jelle, Debyser, Zeger
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5103197/
https://ncbi.nlm.nih.gov/pubmed/27830755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36485
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