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Post-mitotic BET-induced reshaping of integrase quaternary structure supports wild-type MLV integration
The Moloney murine leukemia virus (MLV) is a prototype gammaretrovirus requiring nuclear disassembly before DNA integration. In the nucleus, integration site selection towards promoter/enhancer elements is mediated by the host factor bromo- and extraterminal domain (BET) proteins (bromodomain (Brd)...
Shranjeno v:
| izdano v: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6379647/ https://ncbi.nlm.nih.gov/pubmed/30445610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1157 |
| Oznake: |
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