Saponin-based adjuvants induce cross-presentation in dendritic cells by intracellular lipid body formation

Saponin-based adjuvants (SBAs) are being used in animal and human (cancer) vaccines, as they induce protective cellular immunity. Their adjuvant potency is a factor of inflammasome activation and enhanced antigen cross-presentation by dendritic cells (DCs), but how antigen cross-presentation is indu...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: den Brok, Martijn H., Büll, Christian, Wassink, Melissa, de Graaf, Annemarie M., Wagenaars, Jori A., Minderman, Marthe, Thakur, Mayank, Amigorena, Sebastian, Rijke, Eric O., Schrier, Carla C., Adema, Gosse J.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5103066/
https://ncbi.nlm.nih.gov/pubmed/27819292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13324
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares