Immune Adjuvant Efficacy of CpG Oligonucleotide in Cancer Treatment Is Founded Specifically upon TLR9 Function in Plasmacytoid Dendritic Cells

The differences in function, location, and migratory pattern of conventional dendritic cells (cDC) and plasmacytoid DCs (pDC) not only point to specialized roles in immune responses but also signify additive and interdependent relationships required to clear pathogens. We studied the in vivo require...

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Autori principali: Nierkens, Stefan, den Brok, Martijn H., Garcia, Zacharias, Togher, Susan, Wagenaars, Jori, Wassink, Melissa, Boon, Louis, Ruers, Theo J., Figdor, Carl G., Schoenberger, Stephen P., Adema, Gosse J., Janssen, Edith M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653311/
https://ncbi.nlm.nih.gov/pubmed/21788345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2154
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