The pH-Dependent Trigger in Diphtheria Toxin T Domain Comes with a Safety Latch
Protein-side-chain protonation, coupled to conformational rearrangements, is one way of regulating physiological function caused by changes in protein environment. Specifically, protonation of histidine residues has been implicated in pH-dependent conformational switching in several systems, includi...
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| Publicado no: | Biophys J |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5103022/ https://ncbi.nlm.nih.gov/pubmed/27806276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.09.030 |
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