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Challenges in Predicting Protein-Protein Interactions from Measurements of Molecular Diffusivity

Dynamic light scattering can be used to measure the diffusivity of a protein within a formulation. The dependence of molecular diffusivity on protein concentration (traditionally expressed in terms of the interaction parameter k(D)) is often used to infer whether protein-protein interactions are rep...

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Publicat a:Biophys J
Autors principals: Sorret, Lea L., DeWinter, Madison A., Schwartz, Daniel K., Randolph, Theodore W.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5103004/
https://ncbi.nlm.nih.gov/pubmed/27806265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.09.018
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