Validation of a Rapid, Robust, Inexpensive Screening Method for Detecting the HLA-B(*)58:01 Allele in the Prevention of Allopurinol-Induced Severe Cutaneous Adverse Reactions

The HLA B(*)58:01 allele has been worldwide reported as a pharmacogenetic susceptibility to allopurinol-induced severe cutaneous adverse reactions (SCARs). To prevent these life-threatening conditions, the American College of Rheumatology hingly recommended that the HLA-B(*)58:01 be screened prior t...

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Detalhes bibliográficos
Publicado no:Allergy Asthma Immunol Res
Main Authors: Nguyen, Dinh Van, Vida, Christopher, Chu, Hieu Chi, Fulton, Richard, Li, Jamma, Fernando, Suran L
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2017
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5102839/
https://ncbi.nlm.nih.gov/pubmed/27826965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4168/aair.2017.9.1.79
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