Comparison between the HLA-B(∗)58 : 01 Allele and Single-Nucleotide Polymorphisms in Chromosome 6 for Prediction of Allopurinol-Induced Severe Cutaneous Adverse Reactions

Severe cutaneous adverse drug reactions (SCARs) are life-threatening reactions. The strong association between the HLA-B(∗)58 : 01 allele and allopurinol-induced SCARs is well recognized. Screening for HLA-B(∗)58 : 01 allele before prescribing allopurinol in some populations has been recommended. Se...

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Publicado en:J Immunol Res
Main Authors: Saksit, Niwat, Nakkam, Nontaya, Konyoung, Parinya, Khunarkornsiri, Usanee, Tassaneeyakul, Wongwiwat, Chumworathayi, Pansu, Kanjanawart, Sirimas, Sukasem, Chonlaphat, Sangviroon, Alisara, Pattanacheewapull, Oranuch, Tassaneeyakul, Wichittra
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi 2017
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748122/
https://ncbi.nlm.nih.gov/pubmed/29392141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/2738784
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