HLA-B*13 :01 Is a Predictive Marker of Dapsone-Induced Severe Cutaneous Adverse Reactions in Thai Patients

HLA-B*13:01 allele has been identified as the genetic determinant of dapsone hypersensitivity syndrome (DHS) among leprosy and non-leprosy patients in several studies. Dapsone hydroxylamine (DDS-NHOH), an active metabolite of dapsone, has been believed to be responsible for DHS. However, studies hav...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Satapornpong, Patompong, Pratoomwun, Jirawat, Rerknimitr, Pawinee, Klaewsongkram, Jettanong, Nakkam, Nontaya, Rungrotmongkol, Thanyada, Konyoung, Parinya, Saksit, Niwat, Mahakkanukrauh, Ajanee, Amornpinyo, Warayuwadee, Khunarkornsiri, Usanee, Tempark, Therdpong, Wantavornprasert, Kittipong, Jinda, Pimonpan, Koomdee, Napatrupron, Jantararoungtong, Thawinee, Rerkpattanapipat, Ticha, Wang, Chuang-Wei, Naisbitt, Dean, Tassaneeyakul, Wichittra, Ariyachaipanich, Manasalak, Roonghiranwat, Thapana, Pirmohamed, Munir, Chung, Wen-Hung, Sukasem, Chonlaphat
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8130671/
https://ncbi.nlm.nih.gov/pubmed/34017337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.661135
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