Impact of HLA-B*58:01 allele and allopurinol-induced cutaneous adverse drug reactions: evidence from 21 pharmacogenetic studies

Allopurinol is widely used for hyperuricemia and gouty arthritis, but is associated with cutaneous adverse drug reactions (CADRs). Recently, HLA-B*58:01 allele was identified as a strong genetic marker for allopurinol-induced CADRs in Han Chinese. However, the magnitude of association and diagnosis...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wu, Ran, Cheng, Yi-ju, Zhu, Li-li, Yu, Lei, Zhao, Xue-ke, Jia, Min, Wen, Chang-hui, Long, Xing-zhen, Tang, Ting, He, Ai-juan, Zeng, Yi-yan, Ma, Zun-feng, Zheng, Zhi, Ni, Mu-zi, Cai, Gong-jing
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348437/
https://ncbi.nlm.nih.gov/pubmed/27835909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13250
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