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A Dynamic molecular basis for malfunction in disease mutants of p97/VCP

p97/VCP is an essential, abundant AAA+ ATPase that is conserved throughout eukaryotes, with central functions in diverse processes ranging from protein degradation to DNA damage repair and membrane fusion. p97 has been implicated in the etiology of degenerative diseases and in cancer. Using Nuclear...

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書目詳細資料
發表在:eLife
Main Authors: Schuetz, Anne K, Kay, Lewis E
格式: Artigo
語言:Inglês
出版: eLife Sciences Publications, Ltd 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5102582/
https://ncbi.nlm.nih.gov/pubmed/27828775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.20143
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