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Skewed Expression of the Genes Encoding Epigenetic Modifiers in High-Risk Uveal Melanoma

PURPOSE. Monosomy 3 (M3) or the presence of a specific RNA expression profile, known as class 2, is strongly associated with death from uveal melanoma (UM). Given the important role of epigenetic processes in cancer development and progression, we compared the transcriptional profiles of a selection...

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Bibliografische gegevens
Gepubliceerd in:Invest Ophthalmol Vis Sci
Hoofdauteurs: Herlihy, Naoimh, Dogrusöz, Mehmet, van Essen, T. Huibertus, Harbour, J. William, van der Velden, Pieter A., van Eggermond, Marja C. J. A., Haasnoot, Geert W., van den Elsen, Peter J., Jager, Martine J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Association for Research in Vision and Ophthalmology 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5102441/
https://ncbi.nlm.nih.gov/pubmed/25593028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-15250
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