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Skewed Expression of the Genes Encoding Epigenetic Modifiers in High-Risk Uveal Melanoma

PURPOSE. Monosomy 3 (M3) or the presence of a specific RNA expression profile, known as class 2, is strongly associated with death from uveal melanoma (UM). Given the important role of epigenetic processes in cancer development and progression, we compared the transcriptional profiles of a selection...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Herlihy, Naoimh, Dogrusöz, Mehmet, van Essen, T. Huibertus, Harbour, J. William, van der Velden, Pieter A., van Eggermond, Marja C. J. A., Haasnoot, Geert W., van den Elsen, Peter J., Jager, Martine J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5102441/
https://ncbi.nlm.nih.gov/pubmed/25593028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-15250
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