Pharmacological Targeting of Plasminogen Activator Inhibitor-1 Decreases Vascular Smooth Muscle Cell Migration and Neointima Formation

OBJECTIVE: Plasminogen activator inhibitor-1 (PAI-1), a serine protease inhibitor that promotes and inhibits cell migration, plays a complex and important role in adverse vascular remodeling. Little is known about the effects of pharmacological PAI-1 inhibitors, an emerging drug class, on migration...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Ji, Yan, Weng, Zhen, Fish, Philip, Goyal, Neha, Luo, Mao, Myears, Samantha P., Strawn, Tammy L., Chandrasekar, Bysani, Wu, Jianbo, Fay, William P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5102271/
https://ncbi.nlm.nih.gov/pubmed/27659097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.308344
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