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Plasminogen Activator Inhibitor-1 and Vitronectin Expression Level and Stoichiometry Regulate Vascular Smooth Muscle Cell Migration through Physiological Collagen Matrices

BACKGROUND: Vascular smooth muscle cell (VSMC) migration is a critical process in arterial remodeling. Purified plasminogen activator inhibitor-1 (PAI-1) is reported to both promote and inhibit VSMC migration on 2-dimensional (D) surfaces. OBJECTIVE: To determine the effects of PAI-1 and vitronectin...

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Detalhes bibliográficos
Main Authors: Garg, N., Goyal, N., Strawn, T. L., Wu, J., Mann, K. M., Lawrence, D. A., Fay, W. P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941703/
https://ncbi.nlm.nih.gov/pubmed/20492459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2010.03907.x
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