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Doxycycline Alters Vascular Smooth Muscle Cell Adhesion, Migration, and Reorganization of Fibrillar Collagen Matrices

Remodeling of injured blood vessels is dependent on smooth muscle cells and matrix metalloproteinase activity. Doxycycline is a broad spectrum matrix metalloproteinase inhibitor that is under investigation for the treatment of acute coronary syndromes and aneurysms. In the present study, we examine...

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Detalhes bibliográficos
Main Authors: Franco, Christopher, Ho, Bernard, Mulholland, Diane, Hou, Guangpei, Islam, Muzharul, Donaldson, Katey, Bendeck, Michelle Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606579/
https://ncbi.nlm.nih.gov/pubmed/16651635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050613
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