Doxycycline Alters Vascular Smooth Muscle Cell Adhesion, Migration, and Reorganization of Fibrillar Collagen Matrices

Remodeling of injured blood vessels is dependent on smooth muscle cells and matrix metalloproteinase activity. Doxycycline is a broad spectrum matrix metalloproteinase inhibitor that is under investigation for the treatment of acute coronary syndromes and aneurysms. In the present study, we examine...

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Autors principals: Franco, Christopher, Ho, Bernard, Mulholland, Diane, Hou, Guangpei, Islam, Muzharul, Donaldson, Katey, Bendeck, Michelle Patricia
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2006
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Original Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606579/
https://ncbi.nlm.nih.gov/pubmed/16651635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050613
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