Galectin-3 regulates inflammasome activation in cholestatic liver injury

Macrophage activation is an important feature of primary biliary cholangitis (PBC) pathogenesis and other cholestatic liver diseases. Galectin-3 (Gal3), a pleiotropic lectin, is produced by monocytic cells and macrophages. However, its role in PBC has not been addressed. We hypothesized that Gal3 is...

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Publicado en:FASEB J
Autores principales: Tian, Jijing, Yang, Guoxiang, Chen, Huan-Yuan, Hsu, Daniel K., Tomilov, Alexey, Olson, Kristin A., Dehnad, Ali, Fish, Sarah R., Cortopassi, Gino, Zhao, Bin, Liu, Fu-Tong, Gershwin, M. Eric, Török, Natalie J., Jiang, Joy X.
Formato: Artigo
Lenguaje:Inglês
Publicado: Federation of American Societies for Experimental Biology 2016
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5102125/
https://ncbi.nlm.nih.gov/pubmed/27630169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201600392RR
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