Non-phagocytic Activation of NOX2 is Implicated in Progressive Non-alcoholic Steatohepatitis During Aging

Older patients with obesity/type II DM frequently present with advanced non-alcoholic steatohepatitis (NASH). Whether this is due to specific molecular pathways that accelerate fibrosis during aging, is unknown. Activation of the Src homology 2 domain containing collagen-related (Shc) proteins and r...

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Publicado en:Hepatology
Autores principales: Jiang, Joy X., Fish, Sarah R., Tomilov, Alexey, Li, Yuan, Fan, Weiguo, Dehnad, Ali, Gae, David, Das, Suvarthi, Mozes, Gergely, Charville, Gregory W., Ramsey, Jon, Cortopassi, Gino, Török, NJ
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7478166/
https://ncbi.nlm.nih.gov/pubmed/31950520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.31118
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