Decreased synaptic proteins in neuronal exosomes of frontotemporal dementia and Alzheimer’s disease

Synaptic dysfunction occurs early in senile dementias, presumably as a result of decreased levels of functional synaptic proteins as found in autopsied brains of patients with Alzheimer’s disease (AD) or frontotemporal dementia (FTD). Plasma neuronal-derived exosomes (NDEs) were recovered by precipi...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Goetzl, Edward J., Kapogiannis, Dimitrios, Schwartz, Janice B., Lobach, Iryna V., Goetzl, Laura, Abner, Erin L., Jicha, Gregory A., Karydas, Anna M., Boxer, Adam, Miller, Bruce L.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5102122/
https://ncbi.nlm.nih.gov/pubmed/27601437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201600816R
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