Quercetin-induced apoptosis of HT-29 colon cancer cells via inhibition of the Akt-CSN6-Myc signaling axis

Constitutive photomorphogenesis 9 signalosome (CSN) consists of a total of eight subunits (CSN1-CSN8) in mammalian cells. CSN6 may promote carcinogenesis by positively regulating v-myc avian myelocytomatosis viral oncogene homolog (Myc) and MDM2 proto-oncogene stability, and is regarded as a potenti...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Yang, Lin, Liu, Yanqing, Wang, Mei, Qian, Yayun, Dong, Xiaoyun, Gu, Hao, Wang, Haibo, Guo, Shiyu, Hisamitsu, Tadashi
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101998/
https://ncbi.nlm.nih.gov/pubmed/27748879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.5818
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