Celastrus orbiculatus extract triggers apoptosis and autophagy via PI3K/Akt/mTOR inhibition in human colorectal cancer cells

Celastrus orbiculatus is used as a folk medicine in China for the treatment of numerous diseases. The ethyl acetate extract of Celastrus orbiculatus (COE) also displays a wide range of anti-cancer activities in the laboratory. However, the effectiveness of COE-induced autophagy and its mechanism of...

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Gepubliceerd in:Oncol Lett
Hoofdauteurs: Yang, Lin, Liu, Yanqing, Wang, Mei, Qian, Yayun, Dai, Xiaojun, Zhu, Yaodong, Chen, Jue, Guo, Shiyu, Hisamitsu, Tadashi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: D.A. Spandidos 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5104164/
https://ncbi.nlm.nih.gov/pubmed/27895729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.5213
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