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Synthesis of ST7612AA1, a Novel Oral HDAC Inhibitor, via Radical 
Thioacetic Acid Addition

ABSTRACT: BACKGROUND: In the expanding field of anticancer drugs, HDAC inhibitors are playing an increasingly important role. To date, four/five HDAC inhibitors have been approved by FDA. All these compounds fit the widely accepted HDAC inhibitors pharmacophore model characterized by a cap group, a...

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Dades bibliogràfiques
Publicat a:Curr Bioact Compd
Autors principals: Battistuzzi, Gianfranco, Giannini, Giuseppe
Format: Artigo
Idioma:Inglês
Publicat: Bentham Science Publishers 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101637/
https://ncbi.nlm.nih.gov/pubmed/27917100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1573407212666160504160556
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