Nebulized C1-Esterase Inhibitor does not Reduce Pulmonary Complement Activation in Rats with Severe Streptococcus Pneumoniae Pneumonia

Complement activation plays an important role in the pathogenesis of pneumonia. We hypothesized that inhibition of the complement system in the lungs by repeated treatment with nebulized plasma-derived human C1-esterase inhibitor reduces pulmonary complement activation and subsequently attenuates lu...

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Detaylı Bibliyografya
Yayımlandı:Cell Biochem Biophys
Asıl Yazarlar: de Beer, Friso, Lagrand, Wim, Glas, Gerie J., Beurskens, Charlotte J. P., van Mierlo, Gerard, Wouters, Diana, Zeerleder, Sacha, Roelofs, Joris J. T. H., Juffermans, Nicole P., Horn, Janneke, Schultz, Marcus J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer US 2016
Konular:
Original Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101262/
https://ncbi.nlm.nih.gov/pubmed/27683129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12013-016-0766-1
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