Nebulized C1-Esterase Inhibitor does not Reduce Pulmonary Complement Activation in Rats with Severe Streptococcus Pneumoniae Pneumonia

Complement activation plays an important role in the pathogenesis of pneumonia. We hypothesized that inhibition of the complement system in the lungs by repeated treatment with nebulized plasma-derived human C1-esterase inhibitor reduces pulmonary complement activation and subsequently attenuates lu...

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Detalhes bibliográficos
Publicado no:Cell Biochem Biophys
Main Authors: de Beer, Friso, Lagrand, Wim, Glas, Gerie J., Beurskens, Charlotte J. P., van Mierlo, Gerard, Wouters, Diana, Zeerleder, Sacha, Roelofs, Joris J. T. H., Juffermans, Nicole P., Horn, Janneke, Schultz, Marcus J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2016
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101262/
https://ncbi.nlm.nih.gov/pubmed/27683129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12013-016-0766-1
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