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Nebulized C1-Esterase Inhibitor does not Reduce Pulmonary Complement Activation in Rats with Severe Streptococcus Pneumoniae Pneumonia

Complement activation plays an important role in the pathogenesis of pneumonia. We hypothesized that inhibition of the complement system in the lungs by repeated treatment with nebulized plasma-derived human C1-esterase inhibitor reduces pulmonary complement activation and subsequently attenuates lu...

詳細記述

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書誌詳細
出版年:Cell Biochem Biophys
主要な著者: de Beer, Friso, Lagrand, Wim, Glas, Gerie J., Beurskens, Charlotte J. P., van Mierlo, Gerard, Wouters, Diana, Zeerleder, Sacha, Roelofs, Joris J. T. H., Juffermans, Nicole P., Horn, Janneke, Schultz, Marcus J.
フォーマット: Artigo
言語:Inglês
出版事項: Springer US 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101262/
https://ncbi.nlm.nih.gov/pubmed/27683129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12013-016-0766-1
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