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Antigen-Specific Immune Modulation Targets mTORC1 Function to Drive Chemokine Receptor-Mediated T Cell Tolerance
To contain autoimmunity, pathogenic T cells must be eliminated or diverted from reaching the target organ. Recently, we defined a novel form of T cell tolerance whereby treatment with antigen (Ag) downregulates expression of the chemokine receptor, CXCR3 and prevents diabetogenic Th1 cells from reac...
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| Veröffentlicht in: | J Immunol |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5101142/ https://ncbi.nlm.nih.gov/pubmed/27671108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601032 |
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