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Antigen-Specific Immune Modulation Targets mTORC1 Function to Drive Chemokine Receptor-Mediated T Cell Tolerance

To contain autoimmunity, pathogenic T cells must be eliminated or diverted from reaching the target organ. Recently, we defined a novel form of T cell tolerance whereby treatment with antigen (Ag) downregulates expression of the chemokine receptor, CXCR3 and prevents diabetogenic Th1 cells from reac...

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Dades bibliogràfiques
Publicat a:J Immunol
Autors principals: Chen, Weirong, Wan, Xiaoxiao, Ukah, Tobechukwu K., Miller, Mindy M., Barik, Subhasis, Cattin-Roy, Alexis N., Zaghouani, Habib
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101142/
https://ncbi.nlm.nih.gov/pubmed/27671108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601032
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