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Aging amplifies multiple phenotypic defects in mice with zinc transporter Zip14 (Slc39a14) deletion
Inflammation and zinc dyshomeostasis are two common hallmarks of aging. A major zinc transporter ZIP14 (slc39a14) is upregulated by proinflammatory stimuli, e.g. interleukin-6. We have evaluated the influence of age on the Zip14 KO phenotype using wild-type (WT) and Zip14 knockout (KO) mice. Aging p...
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| Izdano u: | Exp Gerontol |
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| Glavni autori: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5101137/ https://ncbi.nlm.nih.gov/pubmed/27647172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2016.09.013 |
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