Mitochondrial protein functions elucidated by multi-omic mass spectrometry profiling

Mitochondrial dysfunction is associated with many human diseases, including cancer and neurodegeneration, that are often linked to proteins and pathways that are not well-characterized. To begin defining the functions of such poorly characterized proteins, we used mass spectrometry to map the proteo...

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Bibliografske podrobnosti
izdano v:Nat Biotechnol
Main Authors: Stefely, Jonathan A., Kwiecien, Nicholas W., Freiberger, Elyse C., Richards, Alicia L., Jochem, Adam, Rush, Matthew J. P., Ulbrich, Arne, Robinson, Kyle P., Hutchins, Paul D., Veling, Mike T., Guo, Xiao, Kemmerer, Zachary A., Connors, Kyle J., Trujillo, Edna A., Sokol, Jacob, Marx, Harald, Westphall, Michael S., Hebert, Alexander S., Pagliarini, David J., Coon, Joshua J.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101133/
https://ncbi.nlm.nih.gov/pubmed/27669165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3683
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